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  Context Processing in the Hippocampus and Related Circuitry  
  Hippocampal Place Cells and Episodic Memory  
  Neural Circuitry Involved in Instrumental Learning  
     
 

 
  Anterior Cingulate Cortical Role in Attention  
  Limbic Circuitry and Odor Discrimination Learning  
     
 

 
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bullet Learning and Memory
bullet Context Processing
bullet Episodic Memory
bullet Spatial Navigation
bullet Attention



My research falls into the broad category of the neural mediation of learning and memory.  It has become increasingly clear that complex cognitive functions arise from the interactions of multiple interconnected brain regions that comprise functional circuits.  Therefore, I have adopted a systems level approach which involves simultaneously monitoring the neuronal activity in several interconnected brain regions during learning in rodents.  This approach is especially powerful when combined with injections of micro-quantities of chemical inactivating agents directly into discrete brain regions in order to temporarily ‘knock out’ individual components of the circuit.  In this way, the functioning of the healthy and temporarily ‘damaged’ circuits can be compared and the behavioral consequences of the damage can be assessed.  Behavior is the cornerstone of this approach, so neuronal activity is monitored throughout learning using well-controlled training procedures.  Changes in neuronal response patterns can then be specifically associated with learning and learning impairments can be attributed to damage within the circuit and the resulting disruption of neuronal response patterns. 





David M. Smith
252 Uris Hall
Department of Psychology
Cornell University
Ithaca, NY 14852

(607) 255-6390
dms248@cornell.edu
 




I teach Psychology 223, Introduction to Biological Psychology. 

I also teach a seminar entitled Navigation, Memory and Context: What Does the Hippocampus Do?

 

Return to the Laboratory of Neurobiology Home Page David M. Smith, PhD  dms248@cornell.edu