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Learning and Memory |
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Context Processing |
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Episodic Memory |
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Spatial Navigation |
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Attention |
My research falls into the broad category of the neural
mediation of learning and memory. It has become
increasingly clear that complex cognitive functions
arise from the interactions of multiple interconnected
brain regions that comprise functional circuits.
Therefore, I have adopted a systems level approach which
involves simultaneously monitoring the neuronal activity
in several interconnected brain regions during learning
in rodents. This approach is especially powerful when
combined with injections of micro-quantities of chemical
inactivating agents directly into discrete brain regions
in order to temporarily ‘knock out’ individual
components of the circuit. In this way, the functioning
of the healthy and temporarily ‘damaged’ circuits can be
compared and the behavioral consequences of the damage
can be assessed. Behavior is the cornerstone of this
approach, so neuronal activity is monitored throughout
learning using well-controlled training procedures.
Changes in neuronal response patterns can then be
specifically associated with learning and learning
impairments can be attributed to damage within the
circuit and the resulting disruption of neuronal
response patterns.

David M. Smith
252 Uris Hall
Department of Psychology
Cornell University
Ithaca, NY 14852
(607) 255-6390
dms248@cornell.edu

I teach
Psychology 223, Introduction to Biological
Psychology.
I also teach a seminar entitled Navigation, Memory and
Context: What Does the Hippocampus Do? |